4-Trifluoromethylthio Benzyl Amide

4-Trifluoromethylthio Benzyl Amide - Names and Identifiers

Name	4-(Trifluoromethylthio)benzylamine
Synonyms	RARECHEM AL BW 0450 4-(TRIFLUOMETHYLTHIO)BENZYLAMINE 4-trifluoromethylthiobenzylamine 4-(Trifluoromethylthio)benzylamine 4-(TRIFLUOROMETHYLTHIO)BENZYLAMINE 4-Trifluoromethylthio Benzyl Amide 4-TRIFLUOROMETHYLSULFANYL-BENZYLAMINE 1-(4-[(TRIFLUOROMETHYL)THIO]PHENYL)METHANAMINE 1-{4-[(trifluoromethyl)sulfanyl]phenyl}methanamine 2-(Methylsulfonyl)-1-[3-(trifluoromethyl)phenyl]ethanone Ethanone, 2-(methylsulfonyl)-1-[3-(trifluoromethyl)phenyl]-
CAS	128273-56-3
InChI	InChI=1/C8H8F3NS/c9-8(10,11)13-7-3-1-6(5-12)2-4-7/h1-4H,5,12H2

4-Trifluoromethylthio Benzyl Amide - Physico-chemical Properties

Molecular Formula	C8H8F3NS
Molar Mass	207.22
Density	1.310 g/mL (lit.)
Melting Point	224-225 ºC (760 MMHG)
Boling Point	224-225 °C/760 mmHg (lit.)
Flash Point	175°F
Vapor Presure	0.633mmHg at 25°C
pKa	8.66±0.10(Predicted)
Storage Condition	Room Temprature
Sensitive	Stench
Refractive Index	n20/D 1.5040(lit.)

4-Trifluoromethylthio Benzyl Amide - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 - Take off immediately all contaminated clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 3267 8/PG 2
WGK Germany	3
HS Code	29309090
Hazard Note	Corrosive/Stench
Hazard Class	8
Packing Group	II

4-Trifluoromethylthio Benzyl Amide - Introduction

Trifluoromethylthiobenzylamine is an organic compound with the chemical formula C8H7F3NS. The following is a description of its nature, use, preparation and safety information:

Nature:
Trifluoromethylthiobenzylamine is a colorless to light yellow liquid with high volatility. It has a strong pungent odor and is miscible with water and most organic solvents. It can exist stably at room temperature, but it will decompose when heated.

Use:
Trifluoromethylthiobenzylamine is widely used as a catalyst, an intermediate in organic synthesis and a raw material for fungicides. It has good nucleophilicity and basicity, and can be used to synthesize compounds containing trifluoromethylthiobenzylamine groups, such as drugs, dyes, medicines and pesticides.

Preparation Method:
Trifluoromethylthiobenzylamine is usually prepared by the reaction of trifluoromethylmercaptan and benzylamine. The reaction may be carried out in the presence of a quaternary ammonium salt, or the reaction rate may be increased by the addition of an entrainer.

Safety Information:
Trifluoromethylthiobenzylamine has a certain degree of irritation and corrosiveness, and has an irritating effect on the skin and eyes. It is necessary to pay attention to protective measures. Care should be taken during handling and storage to avoid contact with skin and inhalation of vapors. In use should be with good ventilation conditions, avoid contact with fire and heat sources. If accidental inhalation or contact, please seek medical treatment.

Last Update：2024-04-09 19:05:46